5.56x45 NATO Semi Auto Handguns 7 Items

The 5.56x45 NATO Semi-Auto Handgun brings rifle-caliber firepower into a compact and highly maneuverable platform. Designed for tactical applications, personal defense, and range use, these handguns provide the velocity and penetration of a 5.56 rifle round.   

We offer a great selection (7) of 5.56x45 NATO Semi-Auto Handguns from top brands like SIG SAUER, INC., GEISSELE AUTOMATICS LLC, AMERICAN TACTICAL, & CZ USA.  Take advantage of savings on a 5.56x45 NATO Semi-Auto Handgun today, or explore Semi Auto Handguns for more calibers at Brownells.