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45 ACP Semi Auto Handguns 54 Items

45 ACP Semi Auto Handguns Up To 10% Off + Rebate - 54 Products In Stock / 51 Models

The .45 ACP Semi-Auto Handgun has a legendary reputation for stopping power, reliability, and battlefield-proven performance. Designed for defensive use, duty carry, and competition, the .45 ACP delivers heavy-hitting energy with subsonic capabilities, making it a favorite among law enforcement, military personnel, and civilian shooters. While it produces more recoil than 9mm, many shooters appreciate the .45's deep penetration for home defense and personal protection.

We offer a great selection (54) of .45 ACP Semi-Auto Handguns from top brands like COLT, SPRINGFIELD ARMORY, SIG SAUER, INC., & SMITH & WESSON. Our lineup includes classic 1911 pistols with crisp single-action triggers, modern polymer-framed duty guns, and compact carry models for concealed defense. Many feature match-grade barrels, ergonomic grips, and optics-ready slides, making them well-suited for both tactical applications and precision shooting.

Take advantage of savings Up To 10% Off on a .45 ACP Semi-Auto Handgun today, and explore Semi Auto Handguns for more caliber options.

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SMITH & WESSON - SW1911SC E-SERIES 45 ACP SEMI-AUTO HANDGUN SMITH & WESSON - SW1911SC E-SERIES 45 ACP SEMI-AUTO HANDGUN
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(5.0)

$1,469.99

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COLT - SERIES 70 COMPETITION 45 ACP SEMI-AUTO HANDGUN COLT - SERIES 70 COMPETITION 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$927.30 - $1,279.00

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COLT - GOLD CUP NATIONAL MATCH 45 ACP SEMI-AUTO HANDGUN COLT - GOLD CUP NATIONAL MATCH 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$1,261.70

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Product badge SIG SAUER, INC. - 1911 45 ACP SEMI-AUTO HANDGUN SIG SAUER, INC. - 1911 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$1,169.99

$1,299.99

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COLT - 1911 GOVERNMENT CLASSIC 45 ACP SEMI-AUTO HANDGUN COLT - 1911 GOVERNMENT CLASSIC 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$880.00 - $973.50

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COLT - DEFENDER 45 ACP SEMI-AUTO HANDGUN COLT - DEFENDER 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$969.99

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RUGER - SR1911® COMMANDER-STYLE 45 ACP SEMI-AUTO HANDGUN RUGER - SR1911® COMMANDER-STYLE 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$865.99

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SPRINGFIELD ARMORY - 1911 GARRISON 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 GARRISON 45 ACP SEMI-AUTO HANDGUN
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(5.0)

$743.99 - $789.99

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GLOCK - 21 GEN 5 MOS 45 ACP SEMI-AUTO HANDGUN GLOCK - 21 GEN 5 MOS 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$620.00

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GLOCK - 30S 45 ACP SEMI-AUTO HANDGUN GLOCK - 30S 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$546.00

In stock
SPRINGFIELD ARMORY - XD-S MOD.2 OSP 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - XD-S MOD.2 OSP 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$398.99

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SMITH & WESSON - PERFORMANCE CENETER SW1911 45 ACP SEMI-AUTO HANDGUN SMITH & WESSON - PERFORMANCE CENETER SW1911 45 ACP SEMI-AUTO HANDGUN
5 Stars
(4.0)

$1,509.00 - $1,609.99

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SMITH & WESSON - M&P45 SHIELD M2.0 45 ACP SEMI-AUTO HANDGUN SMITH & WESSON - M&P45 SHIELD M2.0 45 ACP SEMI-AUTO HANDGUN
5 Stars
(3.8)

$449.99

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COLT - 1911 GOVERNMENT CLASSIC LIMITED EDITION 45 ACP SEMI-AUTO HANDGUN COLT - 1911 GOVERNMENT CLASSIC LIMITED EDITION 45 ACP SEMI-AUTO HANDGUN
5 Stars
(2.5)

$1,259.99

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COLT - GOLD CUP LITE 45 ACP SEMI-AUTO HANDGUN COLT - GOLD CUP LITE 45 ACP SEMI-AUTO HANDGUN
5 Stars
(2.0)

$1,179.99 - $1,209.99

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WILSON COMBAT - CQB 1911 ELITE FULL SIZE 45 ACP SEMI-AUTO HANDGUN WILSON COMBAT - CQB 1911 ELITE FULL SIZE 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$4,332.00

Online Only - Special Order. Please allow 4-5 weeks additional processing time.
WILSON COMBAT - CQB 1911 FULL SIZE 45 ACP SEMI-AUTO HANDGUN WILSON COMBAT - CQB 1911 FULL SIZE 45 ACP SEMI-AUTO HANDGUN
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(0.0)

$3,533.00

Online Only - Special Order. Please allow 4-5 weeks additional processing time.
WILSON COMBAT - ACP 1911 45 ACP SEMI-AUTO HANDGUN WILSON COMBAT - ACP 1911 45 ACP SEMI-AUTO HANDGUN
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$3,384.00

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DAN WESSON - SPECIALIST OPTIC READY 45 ACP SEMI-AUTO HANDGUN DAN WESSON - SPECIALIST OPTIC READY 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$2,117.50

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DAN WESSON - SPECIALIST COMMANDER BLACK OPTIC READY 45 ACP SEMI-AUTO HANDGUN DAN WESSON - SPECIALIST COMMANDER BLACK OPTIC READY 45 ACP SEMI-AUTO HANDGUN
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(0.0)

$2,117.50

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DAN WESSON - VALOR BLACK 45 ACP SEMI-AUTO HANDGUN DAN WESSON - VALOR BLACK 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$2,117.50

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SPRINGFIELD ARMORY - 1911 TRP CARRY 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 TRP CARRY 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,629.99 - $1,739.00

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SPRINGFIELD ARMORY - 1911 TRP 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 TRP 45 ACP SEMI-AUTO HANDGUN
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$1,629.99 - $1,719.99

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COLT - GOLD CUP TROPHY 45 ACP SEMI-AUTO HANDGUN COLT - GOLD CUP TROPHY 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,649.99

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Product badge SIG SAUER, INC. - 1911-XCARRY 45 ACP SEMI-AUTO HANDGUN WITH ROMEO-X COMPACT SIG SAUER, INC. - 1911-XCARRY 45 ACP SEMI-AUTO HANDGUN WITH ROMEO-X COMPACT
5 Stars
(0.0)

$1,619.99

$1,799.99

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Product badge SIG SAUER, INC. - 1911 X-FULL 45 ACP SEMI-AUTO HANDGUN WITH ROMEO-X COMPACT SIG SAUER, INC. - 1911 X-FULL 45 ACP SEMI-AUTO HANDGUN WITH ROMEO-X COMPACT
5 Stars
(0.0)

$1,619.99

$1,799.99

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DAN WESSON - ECP 45 ACP SEMI-AUTO HANDGUN DAN WESSON - ECP 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,601.60

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COLT - COMBAT UNIT GOVERNMENT 45 ACP SEMI-AUTO HANDGUN COLT - COMBAT UNIT GOVERNMENT 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,449.99

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SMITH & WESSON - SW1911TA E-SERIES TACTICAL RAIL 45 ACP SEMI-AUTO HANDGUN SMITH & WESSON - SW1911TA E-SERIES TACTICAL RAIL 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,409.99

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Product badge SIG SAUER, INC. - 1911 X-FULL EMPEROR SCORPION 45 ACP SEMI-AUTO HANDGUN SIG SAUER, INC. - 1911 X-FULL EMPEROR SCORPION 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,349.99

$1,499.99

In stock
Product badge SIG SAUER, INC. - 1911-XCARRY EMPEROR SCORPION 45 ACP SEMI-AUTO HANDGUN SIG SAUER, INC. - 1911-XCARRY EMPEROR SCORPION 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,349.99

$1,499.99

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Product badge SIG SAUER, INC. - P220 LEGION 45 ACP SEMI-AUTO HANDGUN SIG SAUER, INC. - P220 LEGION 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,169.99 - $1,349.99

$1,299.99

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Product badge SIG SAUER, INC. - 1911-XCARRY 45 ACP SEMI-AUTO HANDGUN SIG SAUER, INC. - 1911-XCARRY 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,349.99

$1,499.99

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Product badge SIG SAUER, INC. - 1911 X-FULL 45 ACP SEMI-AUTO HANDGUN SIG SAUER, INC. - 1911 X-FULL 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,349.99

$1,499.99

In stock
SPRINGFIELD ARMORY - 1911 EMISSARY AOS 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 EMISSARY AOS 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,329.00

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SPRINGFIELD ARMORY - 1911 OPERATOR AOS 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 OPERATOR AOS 45 ACP SEMI-AUTO HANDGUN
5 Stars
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$1,139.00

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COLT - LIGHTWEIGHT COMMANDER 45 ACP SEMI-AUTO HANDGUN COLT - LIGHTWEIGHT COMMANDER 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,027.40

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SMITH & WESSON - SW1911 E-SERIES 45 ACP SEMI-AUTO HANDGUN SMITH & WESSON - SW1911 E-SERIES 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$989.99

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RUGER - SR1911® LIGHTWEIGHT COMMANDER-STYLE 45 ACP SEMI-AUTO HANDGUN RUGER - SR1911® LIGHTWEIGHT COMMANDER-STYLE 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$973.99

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COLT - 1911 SERIES 70 GOVERNMENT MODEL 45 ACP SEMI-AUTO HANDGUN COLT - 1911 SERIES 70 GOVERNMENT MODEL 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$969.99

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SPRINGFIELD ARMORY - 1911 RONIN AOS 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 RONIN AOS 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$909.00

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Product badge SIG SAUER, INC. - P220 ELITE FULL SIZE 45 ACP SEMI-AUTO HANDGUN SIG SAUER, INC. - P220 ELITE FULL SIZE 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$899.99

$999.99

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WALTHER ARMS INC - PPQ 45 ACP SEMI-AUTO HANDGUN WALTHER ARMS INC - PPQ 45 ACP SEMI-AUTO HANDGUN
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$719.00 - $839.00

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SPRINGFIELD ARMORY - 1911 MIL-SPEC 1911 45 ACP CA COMPLIANT SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 MIL-SPEC 1911 45 ACP CA COMPLIANT SEMI-AUTO HANDGUN
5 Stars
(0.0)

$755.99 - $764.99

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SPRINGFIELD ARMORY - DEFEND YOUR LEGACY 1911 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - DEFEND YOUR LEGACY 1911 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$619.99 - $689.99

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GLOCK - 41 GEN 4 MOS 45 ACP SEMI-AUTO HANDGUN GLOCK - 41 GEN 4 MOS 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$666.00

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GLOCK - 41 GEN 4 45 ACP SEMI-AUTO HANDGUN GLOCK - 41 GEN 4 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$596.00

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Product badge SIG SAUER, INC. - P320 NITRON COMPACT 45 ACP SEMI-AUTO HANDGUN SIG SAUER, INC. - P320 NITRON COMPACT 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$584.99

$649.99

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SMITH & WESSON - M&P45 M2.0 45 ACP SEMI-AUTO HANDGUN SMITH & WESSON - M&P45 M2.0 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$559.99

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GLOCK - 21 GEN 3 SF 45 ACP SEMI-AUTO HANDGUN GLOCK - 21 GEN 3 SF 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$546.00

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GLOCK - 30 SF 45 ACP SEMI-AUTO HANDGUN GLOCK - 30 SF 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$546.00

Online Only - In stock
GLOCK - 30 GEN 5 45 ACP SEMI-AUTO HANDGUN GLOCK - 30 GEN 5 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$539.00

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RUGER - RUGER AMERICAN COMPACT 45 ACP SEMI-AUTO HANDGUN RUGER - RUGER AMERICAN COMPACT 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$527.99

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SMITH & WESSON - PERFORMANCE CENTER M&P45 SHIELD M2.0 45 ACP SEMI-AUTO HANDGUN SMITH & WESSON - PERFORMANCE CENTER M&P45 SHIELD M2.0 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$519.99

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COLT - COMBAT ELITE COMMANDER 45 ACP SEMI-AUTO HANDGUN COLT - COMBAT ELITE COMMANDER 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$1,359.99

Out of Stock
COLT - COMBAT COMMANDER 45 ACP SEMI-AUTO HANDGUN COLT - COMBAT COMMANDER 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$1,027.40

Out of Stock
COLT - CUSTOM CARRY LIMITED 45 ACP SEMI-AUTO HANDGUN COLT - CUSTOM CARRY LIMITED 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$2,509.99

Out of Stock
COLT - CUSTOM COMPETITION 45 ACP SEMI-AUTO HANDGUN COLT - CUSTOM COMPETITION 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$2,219.99

Out of Stock
COLT - CUSTOM SHOP CQB 45 ACP SEMI-AUTO HANDGUN COLT - CUSTOM SHOP CQB 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$2,129.99

Out of Stock
DAN WESSON - V-BOB BLACK 45 ACP SEMI-AUTO HANDGUN DAN WESSON - V-BOB BLACK 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$2,117.50

Out of Stock
COLT - M45A1 CMC MARINE 45 ACP SEMI-AUTO HANDGUN COLT - M45A1 CMC MARINE 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,749.00

Out of Stock
COLT - COMBAT UNIT RAIL 45 ACP SEMI-AUTO HANDGUN COLT - COMBAT UNIT RAIL 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,629.00

Out of Stock
COLT - M1911 GOVERNMENT 45 ACP SEMI-AUTO HANDGUN COLT - M1911 GOVERNMENT 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,449.99

Out of Stock
COLT - 1911 GOVERNMENT CLASSIC 45 ACP ROYAL BLUE SEMI-AUTO HANDGUN COLT - 1911 GOVERNMENT CLASSIC 45 ACP ROYAL BLUE SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,449.99

Out of Stock
COLT - COMBAT UNIT OFFICERS 45 ACP SEMI-AUTO HANDGUN COLT - COMBAT UNIT OFFICERS 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,449.99

Out of Stock
COLT - COMBAT ELITE GOVERNMENT 45 ACP SEMI-AUTO HANDGUN COLT - COMBAT ELITE GOVERNMENT 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,449.00

Out of Stock
COLT - COMBAT ELITE DEFENDER 45 ACP SEMI-AUTO HANDGUN COLT - COMBAT ELITE DEFENDER 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,359.99

Out of Stock
COLT - NIGHT COMMANDER 45 ACP SEMI-AUTO HANDGUN COLT - NIGHT COMMANDER 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$1,149.00

Out of Stock
CZ USA - P-10 F OPTIC READY 45 ACP SEMI-AUTO HANDGUN CZ USA - P-10 F OPTIC READY 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$460.90

Out of Stock
HECKLER & KOCH - HK45 V1 45 ACP SEMI-AUTO HANDGUN HECKLER & KOCH - HK45 V1 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$769.00

RUGER - SR1911 LIGHTWEIGHT 45 ACP SEMI-AUTO HANDGUN RUGER - SR1911 LIGHTWEIGHT 45 ACP SEMI-AUTO HANDGUN
5 Stars
(5.0)

$599.99

Product badge SPRINGFIELD ARMORY - 1911 EMISSARY 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 EMISSARY 45 ACP SEMI-AUTO HANDGUN
5 Stars
(1.0)

$969.00

$1,181.99

ED BROWN - SPECIAL FORCES 45 ACP SEMI-AUTO HANDGUN ED BROWN - SPECIAL FORCES 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$3,195.00

RUGER - SR1911® TARGET 45 ACP SEMI-AUTO HANDGUN RUGER - SR1911® TARGET 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$991.99

Product badge SAVAGE ARMS - 1911 GOVERNMENT STYLE 45 ACP SEMI-AUTO HANDGUN SAVAGE ARMS - 1911 GOVERNMENT STYLE 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$977.00

$1,189.00

RUGER - SR1911 45 ACP SEMI-AUTO HANDGUN RUGER - SR1911 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$936.99

SPRINGFIELD ARMORY - 1911 RONIN 45 ACP SEMI-AUTO HANDGUN SPRINGFIELD ARMORY - 1911 RONIN 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$786.99

TAURUS - MODEL 1911 45 ACP SEMI-AUTO HANDGUN TAURUS - MODEL 1911 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$689.99 - $741.99

TAURUS - TH45 45 ACP SEMI-AUTO HANDGUN TAURUS - TH45 45 ACP SEMI-AUTO HANDGUN
5 Stars
(0.0)

$426.99

Products: of 82